Detail of EN13191920


Summary

    Name:LYSC_MELGA
    FullName:Lysozyme C
    Producer Organism:Meleagris gallopavo
    Sequence Length:147
    Mass:16135
    Calculated Isoelectric Point:9.45
    Target:Gram-positive bacteria
    Link:P00703
    Function:Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

Domains

InterPro

50
100
147

  1  []:IPR001916,Glyco_hydro_22
  2  []:IPR019799,Glyco_hydro_22_CS
  3  []:IPR000974,Glyco_hydro_22_lys
  4  []:IPR023346,Lysozyme-like_dom

Structures

  •   1
    135L    Method:X-ray
    Chains:A=19-147
  •   2
    1DZB    Method:X-ray
    Chains:X/Y=19-147
  •   3
    1JEF    Method:X-ray
    Chains:A=19-147
  •   4
    1JSE    Method:X-ray
    Chains:A=19-147
  •   5
    1JTP    Method:X-ray
    Chains:L/M=19-147
  •   6
    1LJN    Method:X-ray
    Chains:A=19-147
  •   7
    1LZ2    Method:X-ray
    Chains:A=19-147
  •   8
    1LZY    Method:X-ray
    Chains:A=19-147
  •   9
    1TEW    Method:X-ray
    Chains:A=19-147
  •   10
    1UAC    Method:X-ray
    Chains:Y=19-147
  •   11
    1XFT    Method:X-ray
    Chains:A=19-147
  •   12
    2LZ2    Method:X-ray
    Chains:A=19-147
  •   13
    3LZ2    Method:X-ray
    Chains:A=19-147

Sequence

MRSLLILVLCFLPLAALGKVYGRCELAAAMKRLGLDNYRGYSLGNWVCAAKFESNFNTHA
TNRNTDGSTDYGILQINSRWWCNDGRTPGSKNLCNIPCSALLSSDITASVNCAKKIASGG
NGMNAWVAWRNRCKGTDVHAWIRGCRL
  BlastP to EnzyBase2

Activity

    No MICs found on enzybiotics database

References

  [1]  Howell P.L.  Structure of hexagonal turkey egg-white lysozyme at 1.65-A resolution.  Acta Crystallogr. D,1995,(51):654-662  [PubMed:15299795]
  [2]  Redfield C.,Dobson C.M.,Bartik K.,  1H-NMR analysis of turkey egg-white lysozyme and comparison with hen egg-white lysozyme.  Eur. J. Biochem.,1993,(215):255-266  [MEDLINE:93345511]
  [3]  Hajdu J.,Petsko G.A.,Parsons M.,Almo S.C.,Howell P.L.,  Structure determination of turkey egg-white lysozyme using Laue diffraction data.  Acta Crystallogr. B,1992,(48):200-207  [MEDLINE:92384991]
  [4]  Wilson A.C.,Krummel B.M.,Weisman L.S.,  Evolutionary shift in the site of cleavage of prelysozyme.  J. Biol. Chem.,1986,(261):2309-2313  [MEDLINE:86111933]
  [5]  Bott R.,Sarma R.,  Crystallographic study of turkey egg-white lysozyme and its complex with a disaccharide.  J. Mol. Biol.,1977,(113):555-565  [MEDLINE:77230499]
  [6]  Speck J.C. Jr.,Larue J.N.,  Turkey egg white lysozyme. Preparation of the crystalline enzyme and investigation of the amino acid sequence.  J. Biol. Chem.,1970,(245):1985-1991  [MEDLINE:70166699]