Detail of EN23409403

Summary

    Name:LYTA_STAAU
    FullName:Autolysin,LytAS
    Producer Organism:Staphylococcus aureus
    Sequence Length:481
    Mass:53819
    Calculated Isoelectric Point:8.84
    Target:S. aureus
    Link:P24556
    Function:Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing cell walls for activity.

Domains

InterPro

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481

  1  []:IPR002502,Amidase_domain
  2  []:IPR007921,CHAP
  3  []:IPR003646,SH3-like_bac
  4  []:IPR013667,SH3_5_bac

GO term prediction

1 GO:0008745, the N-acetylmuramoyl-L-alanine amidase activity
2 GO:0009253, the peptidoglycan catabolic process

Structures

No structs found on enzybiotics database

Sequence

MQAKLTKNEFIERLKTSEGKQFNVDLWYGFQCFDYANAGWKVLFGLLLKGLGAKDIPFAN
NFDGLATVYQNTPDFLAQPGDMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWT
DGIEQPAGVGKKLQDDNMLMISLCGLSVRILKVRQRHDQFNLLHKHPKKETAKPQPKAVE
LKIIKDVVKGYDLPKRGSNPKGIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYV
SGNTVWQALDESQVGWHTANQIGNKYYYGIEVCQSMGADNATFLKNEQATFQECARLLKK
WGLPANRNTIRLHNEFTSTSCPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYM
DGKIPVATVSNESSASSNTVKPVASAWKRNKYGTYYMEESARFTNGNQPITVRKVGPFLS
CPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEI
S

BlastP to EnzyBase2

Activity

No MICs found on enzybiotics database

References

[1] Jayaswal R.K.,Wilkinson B.J.,Wang X., Sequence analysis of a Staphylococcus aureus gene encoding a peptidoglycan hydrolase activity. Gene,1991,(102):105-109 [MEDLINE:91323714]