Detail of EN24605076

Summary

    Name:MEPA_SALTI
    FullName:Penicillin-insensitive murein endopeptidase
    Producer Organism:Salmonella typhi
    Sequence Length:274
    Mass:30235
    Calculated Isoelectric Point:8.62
    Target:E. coli
    Link:Q8Z4Z2
    Function:Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity).

Domains

InterPro

100

150

200

250

274

1 []:IPR009045,Hedgehog/DD-peptidase
2 []:IPR005073,Peptidase_M74

GO term prediction

  1  GO:0004252, the serine-type endopeptidase activity
  2  GO:0006508, the proteolysis
  3  GO:0030288, the outer membrane-bounded periplasmic space

Structures

No structs found on enzybiotics database

Sequence

MKKTAIALLAWFVSSASLAATPWQKITHPVPGAAQSIGSFANGCIIGADTLPVQSDNYQV
MRTDQRRYFGHPDLVMFIQRLSHQAQQRGLGTVLIGDMGMPAGGRFNGGHASHQTGLDVD
IFLQLPKTRWSQAQLLRPQALDLVSRDGKHVVPSRWSSDIASLIKLAAQDNDVTRIFVNP
AIKQQLCLDAGSDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQ
SWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVL

BlastP to EnzyBase2

Activity

No MICs found on enzybiotics database

References

[1] Rose D.J.,Mayhew G.F.,Plunkett G. III,Liou S.-R.,Deng W., Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18. J. Bacteriol.,2003,(185):2330-2337 [MEDLINE:22531367]
[2] Pickard D.,Thomson N.R.,James K.D.,Dougan G.,Parkhill J., Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18. Nature,2001,(413):848-852 [MEDLINE:21534947]