Detail of EN28003671

Summary

    Name:LYTB_STRR6
    FullName:Putative endo-beta-N-acetylglucosaminidase,LytB
    Producer Organism:Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
    Sequence Length:702
    Mass:81900
    Calculated Isoelectric Point:5.09
    Target:S. pneumoniae
    Link:P59206
    Function:Plays an important role in cell wall degradation and cell separation.

Domains

InterPro

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702

  1  []:IPR018337,Cell_wall/Cho-bd_repeat
  2  []:IPR013338,Lysozyme_dom_subfam2
  3  []:IPR002901,Mano_Glyc_endo_b_GlcNAc

GO term prediction

1 GO:0004040, the amidase activity
2 GO:0016787, the hydrolase activity

Structures

No structs found on enzybiotics database

Sequence

MKKVRFIFLALLFFLASPEGAMASDGTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKAD
ANYAENEWLKQGDDYFYLKSGGYMAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATG
AKVIEDWVYDSQYDAWFYIKADGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNAS
GAKVQQGWLFDKQYQSWFYIKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWF
YLKFDGKIAEKEWVYDSHSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYD
SHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMT
ANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKW
LGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLS
GYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLH
FDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALY
LLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYID
RGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD

BlastP to EnzyBase2

Activity

No MICs found on enzybiotics database

References

[1] Burgett S.,Blaszczak L.C.,Arnold J.,Alborn W.E. Jr.,Hoskins J., Genome of the bacterium Streptococcus pneumoniae strain R6. J. Bacteriol.,2001,(183):5709-5717 [MEDLINE:21429245]
[2] Garcia J.L.,Lopez R.,Garcia E.,Gonzalez M.P.,Garcia P., LytB, a novel pneumococcal murein hydrolase essential for cell separation. Mol. Microbiol.,1999,(31):1275-1281 [MEDLINE:99195827]