Detail of EN42419366
Summary
Name:LYS_CLOABFullName:Autolytic lysozyme
Producer Organism:Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Sequence Length:324
Mass:34978
Calculated Isoelectric Point:
Target:
Link:P34020
Function:Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
Domains
InterPro
50
100
150
200
250
300
324
1 [1 - 181]:IPR017853,Glycoside hydrolase, superfamily
2 [190 - 252]:IPR002477,Peptidoglycan binding-like
3 [277 - 320]:IPR002477,Peptidoglycan binding-like
GO term prediction
No GO term predictionStructures
No structs found on enzybiotics databaseSequence
MKGIDIYSGQGSVDFNAVKESGVEVVYIKATEGLTYTDSTYKDFYDGAKNAGLKIGFYHY LRANDPTSEAEHFFNTISGLSLDCKCAIDVEVTLGQSIDQISSNVRKFADYLINKGLDVC VYTYTNFYKDNLNSTVKDLPLWIAEYGVSKPNIDASYVGFQYSDSGSVNGISGSADLDEF SEGILVGGTVVIDPGQGGDDNIKAIQQDLNILLKRGLEVDGIEGPETEAAIKDFQSIMGL TVDGIWGTNTSGAAQQIFSRPLDGVAYPHYEYATRYIQYRVGASVDGTFGSGTKAKVAAW QSNQGLMADGVVGSATWSKLLDEN
Activity
No MICs found on enzybiotics databaseReferences
[1] Zeng Q.,Makarova K.S.,Omelchenko M.V.,Breton G.,Noelling J., Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum. J. Bacteriol.,2001,(183):4823-4838 [PubMed:11466286][2] Soucaille P.,Goma G.,Canard B.,Croux C., Purification and characterization of an extracellular muramidase of Clostridium acetobutylicum ATCC 824 that acts on non-N-acetylated peptidoglycan. Appl. Environ. Microbiol.,1992,(58):1075-1081 [PubMed:1599233]
[3] Soucaille P.,Goma G.,Canard B.,Croux C., Autolysis of Clostridium acetobutylicum ATCC 824. J. Gen. Microbiol.,1992,(138):861-869 [PubMed:1645127]
[4] Garcia J.L.,Croux C., Sequence of the lyc gene encoding the autolytic lysozyme of Clostridium acetobutylicum ATCC824: comparison with other lytic enzymes. Gene,1991,(104):25-31 [PubMed:1916274]