Detail of EN42419366


Summary

    Name:LYS_CLOAB
    FullName:Autolytic lysozyme
    Producer Organism:Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
    Sequence Length:324
    Mass:34978
    Calculated Isoelectric Point:
    Target:
    Link:P34020
    Function:Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Domains

IPR017853:1 - 181
IPR002477:190 - 252
IPR002477:277 - 320
InterPro

50
100
150
200
250
300
324

  1  [1 - 181]:IPR017853,Glycoside hydrolase, superfamily
  2  [190 - 252]:IPR002477,Peptidoglycan binding-like
  3  [277 - 320]:IPR002477,Peptidoglycan binding-like

GO term prediction

    No GO term prediction

Structures

    No structs found on enzybiotics database

Sequence

MKGIDIYSGQGSVDFNAVKESGVEVVYIKATEGLTYTDSTYKDFYDGAKNAGLKIGFYHY
LRANDPTSEAEHFFNTISGLSLDCKCAIDVEVTLGQSIDQISSNVRKFADYLINKGLDVC
VYTYTNFYKDNLNSTVKDLPLWIAEYGVSKPNIDASYVGFQYSDSGSVNGISGSADLDEF
SEGILVGGTVVIDPGQGGDDNIKAIQQDLNILLKRGLEVDGIEGPETEAAIKDFQSIMGL
TVDGIWGTNTSGAAQQIFSRPLDGVAYPHYEYATRYIQYRVGASVDGTFGSGTKAKVAAW
QSNQGLMADGVVGSATWSKLLDEN
  BlastP to EnzyBase2

Activity

    No MICs found on enzybiotics database

References

  [1]  Zeng Q.,Makarova K.S.,Omelchenko M.V.,Breton G.,Noelling J.,  Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum.  J. Bacteriol.,2001,(183):4823-4838  [PubMed:11466286]
  [2]  Soucaille P.,Goma G.,Canard B.,Croux C.,  Purification and characterization of an extracellular muramidase of Clostridium acetobutylicum ATCC 824 that acts on non-N-acetylated peptidoglycan.  Appl. Environ. Microbiol.,1992,(58):1075-1081  [PubMed:1599233]
  [3]  Soucaille P.,Goma G.,Canard B.,Croux C.,  Autolysis of Clostridium acetobutylicum ATCC 824.  J. Gen. Microbiol.,1992,(138):861-869  [PubMed:1645127]
  [4]  Garcia J.L.,Croux C.,  Sequence of the lyc gene encoding the autolytic lysozyme of Clostridium acetobutylicum ATCC824: comparison with other lytic enzymes.  Gene,1991,(104):25-31  [PubMed:1916274]