Detail of EN62874310

Summary

    Name:O56788_9CAUD
    FullName:phage Twort lysin,PlyTW
    Producer Organism:Staphylococcus phage Twort
    Sequence Length:467
    Mass:53271
    Calculated Isoelectric Point:9.54
    Target:S. aureus
    Link:O56788
    Function:null

Domains

IPR007921:4-141

IPR002502:172-343

IPR003646:355-382

InterPro

100

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250

300

350

400

450

467

  1  [4-141]:IPR007921,CHAP domain
  2  [172-343]:IPR002502,N-acetylmuramoyl-L-alanine amidase domain
  3  [355-382]:IPR003646,SH3-like domain, bacterial-type

GO term prediction

1 GO:0008745, the N-acetylmuramoyl-L-alanine amidase activity
2 GO:0009253, the peptidoglycan catabolic process

Structures

No structs found on enzybiotics database

Sequence

MKTLKQAESYIKSKVNTGTDFDGLYGYQCMDLAVDYIYHVTDGKIRMWGNAKDAINNSFG
GTATVYKNYPAFRPKYGDVVVWTTGNFATYGHIAIVTNPDPYGDLQYVTVLEQNWNGNGI
YKTELATIRTHDYTGITHFIRPNFATESSVKKKDTKKKPKPSNRDGINKDKIVYDRTNIN
YNMVKRGYNPVGVILHNDAGSMTGLQYKNNLQNAGYNRWAQGIAHSYISEGQVWQALGES
RIAWHCANQWGNKNLYGIEICQSMTASDEQFLKNEQTAFYEASRMLKKWGLKPDKNTVRL
HMEYYQTACPHRSMKLHVGKDPTKTSITQADIEKLKEYFIKQIKMYYEGKTPVPTVVNQK
AKTKPVKQSSTSGWNVNNYGTYYKSESATFKCTARQGIVTRYTGPFTTCPQAGVLYYGQS
VTYDTVCKQDGYVWISWTTNGGQDVWMPVRTWDKNTDIMGQLWGDIY

BlastP to EnzyBase2

Activity

No MICs found on enzybiotics database

References

[1] Pelletier J.,Gros P.,DuBow M.,Liu J.,Kwan T., The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages. Proc. Natl. Acad. Sci. U.S.A.,2005,(102):5174-5179 [PubMed:15788529]
[2] Scherer S.,Maier S.K.,Wendlinger G.,Gaeng S.,Loessner M.J., The two-component lysis system of Staphylococcus aureus bacteriophage Twort: a large TTG-start holin and an associated amidase endolysin. FEMS Microbiol. Lett.,1998,(162):265-274 [MEDLINE:98291432]