Detail of EN75356455

Summary

    Name:Q9MCC8_9CAUD
    FullName:phage A2 lysin
    Producer Organism:Lactobacillus phage A2
    Sequence Length:350
    Mass:37436
    Calculated Isoelectric Point:4.96
    Target:lactococci, pediococci, lactobacilli, listeriae and some enterococci
    Link:Q9MCC8
    Function:null

Domains

InterPro

100

150

200

250

300

350

1 []:IPR002502,Amidase_domain

GO term prediction

1 GO:0008745, the N-acetylmuramoyl-L-alanine amidase activity
2 GO:0009253, the peptidoglycan catabolic process

Structures

No structs found on enzybiotics database

Sequence

MSYTINKEFALGANEGSSQVANRLYIILHDVGAESGARANAAYFKNNISAEIAYTAFVVG
DGGQVYQVGEPGYVQWGAGTVANANSPVQIELGHTSDPETFKKDYAVYIELARDMAARYG
IPTSLDAGGAGTPGIKSHLWVTQHIWGDHTDPYGYLARWGITKEKLAADLANGTTTVDAS
TSAPATQSTRPQATVSGNVNATYGLHLLGGSWLDEVTNFGSGDNGFAGMPNHQHDLLYIR
VDHGSVKYRVHTVQSGWLDWVTKGDRNDTVNGCAGIAGEAIDGVQIIFLTPAGEPYQQAY
YRSQTTQRAGWLGVVCDDGTSLPQYTGTYAGLFGEPLDRLQIGISSINPF

BlastP to EnzyBase2

Activity

No MICs found on enzybiotics database

References

  [1]  Ladero V.,Garcia P.,Suarez J.,van Sinderen D.,Proux C.,  The dilemma of phage taxonomy illustrated by comparative genomics of Sfi21-like Siphoviridae in lactic acid bacteria.  J. Bacteriol.,2002,(184):6026-6036  [MEDLINE:22262118]
  [2]  Suarez J.E.,Moscoso M.,  Characterization of the DNA replication module of bacteriophage A2 and use of its origin of replication as a defense against infection during milk fermentation by Lactobacillus casei.  Virology,2000,(273):101-111  [MEDLINE:20351728]
  [3]  Suarez J.E.,Alonso J.C.,Ladero V.,Garcia P.,  Cooperative interaction of CI protein regulates lysogeny of Lactobacillus casei by bacteriophage A2.  J. Virol.,1999,(73):3920-3929  [MEDLINE:99214330]
  [4]  Suarez J.E.,Alonso J.C.,Garcia P.,Ladero V.,  A2 Cro, the lysogenic cycle repressor, specifically binds to the genetic switch region of Lactobacillus casei bacteriophage A2.  Virology,1999,(262):222-229  [:]
  [5]  Alvarez M.A.,Herrero M.,Bascaran V.,Garcia P.,Ladero V.,  Identification of the repressor-encoding gene of the Lactobacillus bacteriophage A2.  J. Bacteriol.,1998,(180):3474-3476  [MEDLINE:98317291]
  [6]  Suarez J.E.,Herrero M.,Alvarez M.A.,  The site-specific recombination system of the Lactobacillus species bacteriophage A2 integrates in gram-positive and gram-negative bacteria.  Virology,1998,(250):185-193  [MEDLINE:98445458]
  [7]  Suarez J.E.,Alonso J.C.,Garcia P.,  Molecular analysis of the cos region of the Lactobacillus casei bacteriophage A2. Gene product 3, gp3, specifically binds to its downstream cos region.  Mol. Microbiol.,1997,(23):505-514  [MEDLINE:97197195]