Detail of EN78717945

Summary

    Name:Q37969_9CAUD
    FullName:phage phiLC3 lysin
    Producer Organism:Lactococcus phage phiLC3
    Sequence Length:429
    Mass:46260
    Calculated Isoelectric Point:9.36
    Target:S. agalactiae, groups A, C, G, L streptococci
    Link:Q37969
    Function:null

Domains

InterPro

100

150

200

250

300

350

400

429

  1  []:IPR002053,Glyco_hydro_25
  2  []:IPR018077,Glyco_hydro_fam25_subgr
  3  []:IPR013781,Glyco_hydro_subgr_catalytic
  4  []:IPR017853,Glycoside_hydrolase_SF
  5  []:IPR018392,Peptidoglycan-bd_lysin
  6  []:IPR002482,Peptidoglycan-bd_Lysin_subgr

GO term prediction

  1  GO:0003796, the lysozyme activity
  2  GO:0009253, the peptidoglycan catabolic process
  3  GO:0016998, the cell wall macromolecule catabolic process
  4  GO:0005975, the carbohydrate metabolic process

Structures

No structs found on enzybiotics database

Sequence

MKRLIKKSAIGMFAFFVVAASGPVFAAVGDQGVDWSKYNGTYGNFGYAHDKFAFSQIGGT
YGGTFVDQATYETQVASAIAQGKRAHTYIWYQVGGSQEVAKAALDRYLPKIQTPKNSIVA
LDYEGGASGNKQANTDAILYGMRRVKAAGYTPMYYSYKPYTLANVNYKQIIKEFPKSLWI
AAYPNYEVTPVPNYSFFPSMDGISVFQFTSTYVAGGLDGNVDLTGITGNGYGKQKGQEVK
PNTATPAIENGKEANEVKGNDVEVGMTVKVNFGAKNYATGETIPQWVKGQPHKIIQKNGD
TVLLDGIMSWLSVHDVETIDASTSQPTTPAKSYIVKQGDTLSGIASNLGTNWQELARQNS
LSNPNMIYSGQVISLTGGQSGATARTYTVQSGDNLSSIARRLGTTVQSLVSMNGISNPNL
IYAGQTLNY

BlastP to EnzyBase2

Activity

No MICs found on enzybiotics database

References

  [1]  Nes I.F.,Lunde M.,Godager L.,Blatny J.M.,  Complete genome sequence of the Lactococcus lactis temperate phage phiLC3: comparative analysis of phiLC3 and its relatives in lactococci and streptococci.  Virology,2004,(318):231-244  [PubMed:14972551]
  [2]  Lunde M.,Risoen P.A.,Rosenhaven E.M.,Ventura M.,Blatny J.M.,  Transcriptional analysis of the genetic elements involved in the lysogeny/lysis switch in the temperate lactococcal bacteriophage phiLC3, and identification of the Cro-like protein ORF76.  Mol. Genet. Genomics,2003,(269):487-498  [MEDLINE:22766050]
  [3]  Nes I.F.,Lunde M.,Lillehaug D.,Risoen P.A.,Blatny J.M.,  Analysis of a regulator involved in the genetic switch between lysis and lysogeny of the temperate Lactococcus lactis phage phi LC3.  Mol. Genet. Genomics,2001,(265):189-197  [MEDLINE:21263014]
  [4]  Birkeland N.K.,Nes I.F.,Lillehaug D.,  A highly efficient and stable system for site-specific integration of genes and plasmids into the phage phiLC3 attachment site (attB) of the Lactococcus lactis chromosome.  Gene,1997,(188):129-136  [MEDLINE:97254461]
  [5]  Birkeland N.K.  Cloning, molecular characterization, and expression of the genes encoding the lytic functions of lactococcal bacteriophage phi LC3: a dual lysis system of modular design.  Can. J. Microbiol.,1994,(40):658-665  [MEDLINE:95007252]
  [6]  Lonneborg A.M.,Birkeland N.K.,  The cos region of lactococcal bacteriophage phi LC3.  DNA Seq.,1993,(4):211-214  [MEDLINE:94214173]
  [7]  Birkeland N.K.,Lillehaug D.,  Characterization of genetic elements required for site-specific integration of the temperate lactococcal bacteriophage phi LC3 and construction of integration-negative phi LC3 mutants.  J. Bacteriol.,1993,(175):1745-1755  [MEDLINE:93194800]
  [8]  Birkeland N.K.,Lindqvist B.,Lillehaug D.,  Characterization of phiLC3, a Lactococcus lactis subsp. cremoris temperature bacteriophage with cohesive single-stranded DNA ends.  Appl. Environ. Microbiol.,1991,(57):3206-3211  [MEDLINE:92143594]