Detail of EN86525491

Summary

    Name:AEPE_BPA50
    FullName:phage A500 lysin,Ply500
    Producer Organism:Listeria phage A500
    Sequence Length:289
    Mass:33424
    Calculated Isoelectric Point:9.94
    Target:B. megaterium
    Link:Q37979
    Function:Cell wall lytic enzyme.

Domains

InterPro

100

150

200

250

289

1 []:IPR009045,Hedgehog/DD-peptidase
2 []:IPR003709,Pept_M15B/M15C

GO term prediction

1 GO:0008233, the peptidase activity
2 GO:0006508, the proteolysis

Structures

1
2VO9Method:X-ray
Chains:A/B/C=1-167

Sequence

MALTEAWLIEKANRKLNAGGMYKITSDKTRNVIKKMAKEGIYLCVAQGYRSTAEQNALYA
QGRTKPGAIVTNAKGGQSNHNYGVAVDLCLYTNDGKDVIWESTTSRWKKVVAAMKAEGFK
WGGDWKSFKDYPHFELCDAVSGEKIPAATQNTNTNSNRYEGKVIDSAPLLPKMDFKSSPF
RMYKVGTEFLVYDHNQYWYKTYIDDKLYYMYKSFCDVVAKKDAKGRIKVRIKSAKDLRIP
VWNNIKLNSGKIKWYAPNVKLAWYNYRRGYLELWYPNDGWYYTAEYFLK

BlastP to EnzyBase2

Activity

No MICs found on enzybiotics database

References

[1] Scherer S.,Wendlinger G.,Loessner M.J., Heterogeneous endolysins in Listeria monocytogenes bacteriophages: a new class of enzymes and evidence for conserved holin genes within the siphoviral lysis cassettes. Mol. Microbiol.,1995,(16):1231-1241 [MEDLINE:96020653]