Detail of EN89057414


Summary

    Name:ALYS_BPDP1
    FullName:phage Dp-1 lysin,Pal
    Producer Organism:Pneumococcus phage Dp-1
    Sequence Length:296
    Mass:34453
    Calculated Isoelectric Point:4.74
    Target:S. pneumoniae
    Link:O03979
    Function:Lysis of bacterial host cell wall.

Domains

InterPro

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296

  1  []:IPR018337,Cell_wall/Cho-bd_repeat
  2  []:IPR008044,Phage_SFi21_lysin

GO term prediction

    No GO term prediction

Structures

    No structs found on enzybiotics database

Sequence

MGVDIEKGVAWMQARKGRVSYSMDFRDGPDSYDCSSSMYYALRSAGASSAGWAVNTEYMH
AWLIENGYELISENAPWDAKRGDIFIWGRKGASAGAGGHTGMFIDSDNIIHCNYAYDGIS
VNDHDERWYYAGQPYYYVYRLTNANAQPAEKKLGWQKDATGFWYARANGTYPKDEFEYIE
ENKSWFYFDDQGYMLAEKWLKHTDGNWYWFDRDGYMATSWKRIGESWYYFNRDGSMVTGW
IKYYDNWYYCDATNGDMKSNAFIRYNDGWYLLLPDGRLADKPQFTVEPDGLITAKV
  BlastP to EnzyBase2

Activity

    No MICs found on enzybiotics database

References

  [1]  Fischetti V.A.,Nelson D.,Loeffler J.M.,  Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase.  Science,2001,(294):2170-2172  [MEDLINE:21605543]
  [2]  Garcia P.,Lopez R.,Garcia J.L.,Sheehan M.M.,  The lytic enzyme of the pneumococcal phage Dp-1: a chimeric lysin of intergeneric origin.  Mol. Microbiol.,1997,(25):717-725  [MEDLINE:98025469]