Drug Summary

  Drug name:  exemestane
  Chemical name:  exemestane
  Formula:  C₂₀H₂₄O₂
  Weight:   296.4034
  CAS no:  107868-30-4
  DrugBank link:  DB00990
  Description:  Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation.
  Indication:  For the treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.