Drug Summary

  Drug name:  nordihydroguaiaretic acid
  Chemical name:  nordihydroguaiaretic acid
  Formula:  C₁₈H₂₂O₄
  Weight:   302.3649
  CAS no:  27686-84-6
  DrugBank link:  DB00179
  Description:  A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]
  Indication:  Used for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).