Drug Summary


  Drug name:  ciclosporin
  Chemical name:  cyclosporine A
  Formula:  C62H111N11O1
  Weight:   1202.6112
  CAS no:  59865-13-3
  DrugBank link:  DB00091
  Description:  A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. Cyclosporine is produced as a metabolite by the fungus species Cordyceps militaris. (From Martindale, The Extra Pharmacopoeia, 30th ed).
  Indication:  For treatment of transplant (kidney, liver, and heart) rejection, rheumatoid arthritis, severe psoriasis.