Drug Summary


  Drug name:  azathioprine
  Chemical name:  azathioprine, USP
  Formula:  C9H7N7O2  Weight:   277.263
  CAS no:  446-86-6
  DrugBank link:  DB00993
  Description:  An immunosuppressive antimetabolite pro-drug. It is an imidazolyl derivative of 6-mercaptopurine and many of its biological effects are similar to those of the parent compound. Azathioprine is converted into 6-mercaptopurine in the body where it blocks purine metabolism and DNA synthesis.
  Indication:  For use in rheumatoid arthritis, preventing renal transplant rejection, Crohn's disease, and colitis.