Drug Summary
Drug name: hydroxyzine Chemical name: Hydroxyzine dihydrochloride Formula: C21H27ClN2O2 Weight: 374.904 CAS no: 68-88-2 DrugBank link: DB00557 Description: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite cetirizine, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative. [PubChem] Indication: For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.