Drug Summary


  Drug name:  loperamide
  Chemical name:  Loperamide hydrochloride
  Formula:  C29H33ClN2O2
  Weight:   477.038
  CAS no:  53179-11-6
  DrugBank link:  DB00836
  Description:  One of the long-acting synthetic antidiarrheals; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally. [PubChem]
  Indication:  For the control and symptomatic relief of acute nonspecific diarrhea and of chronic diarrhea associated with inflammatory bowel disease or gastroenteritis. Also used for reducing the volume of discharge from ileostomies.