Drug Summary


  Drug name:  labetalol
  Chemical name:  Labetalol hydrochloride
  Formula:  C19H24N2O3  Weight:   328.4055
  CAS no:  36894-69-6
  DrugBank link:  DB00598
  Description:  Blocker of both alpha- and beta-adrenergic receptors that is used as an antihypertensive. [PubChem]
  Indication:  For the management of hypertension (alone or in combination with other classes of antihypertensive agents), as well as chronic stable angina pectoris and sympathetic overactivity syndrome associated with severe tetanus. Labetalol is used parenterally for immediate reduction in blood pressure in severe hypertension or in hypertensive crises when considered an emergency, for the control of blood pressure in patients with pheochromocytoma and pregnant women with preeclampsia, and to produce controlled hypotension during anesthesia to reduce bleeding resulting from surgical procedures.