Drug Summary

  Drug name:  etacrynic acid
  Chemical name:  Ethacrynic acid
  Formula:  C₁₃H₁₂Cl₂O_{4<
  Weight:   303.138
  CAS no:  58-54-8
  DrugBank link:  DB00903
  Description:  A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic. [PubChem]
  Indication:  For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.}