Drug Summary
Drug name: dapsone Chemical name: Dapsone Formula: C12H12N2O2 Weight: 248.301 CAS no: 80-08-0 DrugBank link: DB00250 Description: A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8) Indication: For the treatment and management of leprosy and dermatitis herpetiformis.