Drug Summary


  Drug name:  dapsone
  Chemical name:  Dapsone
  Formula:  C12H12N2O2  Weight:   248.301
  CAS no:  80-08-0
  DrugBank link:  DB00250
  Description:  A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
  Indication:  For the treatment and management of leprosy and dermatitis herpetiformis.