Drug Summary


  Drug name:  imipenem
  Chemical name:  Imipenem
  Formula:  C12H17N3O4  Weight:   299.346
  CAS no:  74431-23-5
  DrugBank link:  DB01598
  Description:  Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with cilastatin, a renal dipeptidase inhibitor. [PubChem]
  Indication:  For the treatment of bacterial infections caused by susceptible bacteria.