Drug Summary

  Drug name:  dacarbazine
  Chemical name:  Dacarbazine
  Formula:  C₆H₁₀N₆O
  Weight:   182.1832
  CAS no:  4342-03-4
  DrugBank link:  DB00851
  Description:  An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
  Indication:  For the treatment of metastatic malignant melanoma. In addition, dacarbazine is also indicated for Hodgkin's disease as a secondary-line therapy when used in combination with other antineoplastic agents.