Drug Summary

  Drug name:  dantrolene
  Chemical name:  Dantrolene sodium salt
  Formula:  C₁₄H₁₀N₄O_{5  Weight:   314.253
  CAS no:  7261-97-4
  DrugBank link:  DB01219
  Description:  Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
  Indication:  For use, along with appropriate supportive measures, for the management of the fulminant hypermetabolism of skeletal muscle characteristic of malignant hyperthermia crises in patients of all ages. Also used preoperatively, and sometimes postoperatively, to prevent or attenuate the development of clinical and laboratory signs of malignant hyperthermia in individuals judged to be malignant hyperthermia susceptible.}