Drug Summary

  Drug name:  digoxin
  Chemical name:  Digoxin
  Formula:  C₄₁H₆₄O₁₄
  Weight:   780.9385
  CAS no:  20830-75-5
  DrugBank link:  DB00390
  Description:  A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone digoxigenin. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
  Indication:  For the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.