Drug Summary

  Drug name:  vigabatrin
  Chemical name:  Vigabatrin
  Formula:  C₆H₁₁NO₂
  Weight:   129.157
  CAS no:  60643-86-9
  DrugBank link:  DB01080
  Description:  An analogue of gamma-aminobutyric acid, vigabatrin is an irreversible inhibitor of 4-aminobutyrate transaminase, the enzyme responsible for the catabolism of gamma-aminobutyric acid. (From Martindale The Extra Pharmacopoeia, 31st ed). Off-label uses include treatment of cocaine dependence.
  Indication:  For use as an adjunct in treatment resistant epilepsy, refractory complex partial seizures, and secondary generalized seizures. It is also used as monotherapy in infantile spasms in West syndrome.