Drug Summary

  Drug name:  selegiline
  Chemical name:  Selegiline hydrochloride
  Formula:  C₁₃H₁₇N
  Weight:   187.2808
  CAS no:  14611-51-9
  DrugBank link:  DB01037
  Description:  A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson’s disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl. [PubChem]
  Indication:  Monotherapy for initial treatment of Parkinson's disease, as well as an adjunct therapy in patients with a decreased response to levodopa/carbadopa. Also used for the palliative treatment of mild to moderate Alzheimer's disease and at higher doses, for the treatment of depression.