Drug Summary

  Drug name:  rifampicin
  Chemical name:  Rifampicin
  Formula:  C₄₃H₅₈N₄O_{12<
  Weight:   822.9402
  CAS no:  13292-46-1
  DrugBank link:  DB01045
  Description:  A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)
  Indication:  For the treatment of Tuberculosis and Tuberculosis-related mycobacterial infections.}