Drug Summary

  Drug name:  leflunomide
  Chemical name:  Leflunomide
  Formula:  C₁₂H₉F₃N_{2  Weight:   270.2073
  CAS no:  75706-12-6
  DrugBank link:  DB01097
  Description:  Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
  Indication:  For the management of the signs and symptoms of active rheumatoid arthritis (RA) to improve physical function and to slow the progression of structural damage associated with the disease. Has also been used for the prevention of acute and chronic rejection in recipients of solid organ trasnplants and is designated by the FDA as an orphan drug for this use.}