Drug Summary

  Drug name:  podophyllotoxin
  Chemical name:  Podophyllotoxin
  Formula:  C₂₂H₂₂O₈
  Weight:   414.4053
  CAS no:  518-28-5
  DrugBank link:  DB01179
  Description:  A lignan (lignans) found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. [PubChem]
  Indication:  For treatment of external genital warts (Condyloma acuminatum).