Drug Summary

  Drug name:  demeclocycline
  Chemical name:  Demeclocycline hydrochloride
  Formula:  C₂₁H₂₁ClN₂O_{8
  Weight:   464.853
  CAS no:  127-33-3
  DrugBank link:  DB00618
  Description:  A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time. [PubChem]
  Indication:  Used primarily to treat Lyme disease, acne, and bronchitis. Also indicated (but rarely used) to treat urinary tract infections, gum disease, malaria, and other bacterial infections such as gonorrhea and chlamydia. One of its other registered uses is the treatment of hyponatremia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective.}