Drug Summary


  Drug name:  cefazolin
  Chemical name:  Cefazolin sodium salt
  Formula:  C14H14N8O4  Weight:   454.507
  CAS no:  25953-19-9
  DrugBank link:  DB01327
  Description:  A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine. [PubChem]
  Indication:  Mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. May be used for surgical prophylaxis; if required metronidazole may be added to cover B. fragilis.