Drug Summary

  Drug name:  molindone
  Chemical name:  Molindone hydrochloride
  Formula:  C₁₆H₂₄N₂O_{2  Weight:   276.374
  CAS no:  7416-34-4
  DrugBank link:  DB01618
  Description:  An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of clozapine. (From AMA Drug Evaluations Annual, 1994, p283)
  Indication:  Molindone is used for the management of the manifestations of psychotic disorders.}