Drug Summary
Drug name: proguanil Chemical name: Proguanil hydrochloride Formula: C11H16ClN5 Weight: 253.731 CAS no: 500-92-5 DrugBank link: DB01131 Description: Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, Plasmodium falciparum and Plasmodium vivax, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite. Indication: For the causal prevention and suppression of malaria caused by susceptible strains of P. falciparum and other species of Plasmodium found in some geographical areas of the world.