Drug Summary

  Drug name:  netilmicin
  Chemical name:  Netilmicin sulfate
  Formula:  C₂₁H₄₁N₅O_{7  Weight:   475.5795
  CAS no:  56391-56-1
  DrugBank link:  DB00955
  Description:  Netilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity. [PubChem] Netilmicin inhibits protein synthesis in susceptible organisms by binding to the bacterial 30S ribosomal subunit and interfering with mRNA binding and the acceptor tRNA site. The bactericidal effect of netilmiicin is not fully understood.
  Indication:  For the treatment of bacteremia, septicaemia, respiratory tract infections, skin and soft-tissue infection, burns, wounds, and peri-operative infections caused by susceptible strains.}