Drug Summary

  Drug name:  doxazosin
  Chemical name:  Doxazosin mesylate
  Formula:  C₂₃H₂₅N₅O_{5  Weight:   451.4751
  CAS no:  74191-85-8
  DrugBank link:  DB00590
  Description:  Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. It may be used to mild to moderate hypertension and in the management of symptomatic benign prostatic hyperplasia (BPH). α1-Receptors mediate contraction and hypertrophic growth of smooth muscle cells. Antagonism of these receptors leads to smooth muscle relaxation in the peripheral vasculature and prostate gland.
  Indication:  For treatment and management of mild to moderate hypertension and urinary obstruction symptoms caused by BPH.}