Drug Summary

  Drug name:  azacitidine
  Chemical name:  Azacytidine-5
  Formula:  C₈H₁₂N₄O_{5  Weight:   244.2047
  CAS no:  320-67-2
  DrugBank link:  DB00928
  Description:  A pyrimidine nucleoside analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent. [PubChem]
  Indication:  For treatment of patients with the following French-American-British myelodysplastic syndrome subtypes: refractory anemia or refractory anemia with ringed sideroblasts (if accompanied by neutropenia or thrombocytopenia or requiring transfusions), refractory anemia with excess blasts, refractory anemia with excess blasts in transformation (now classified as acute myelogenous leukemia with multilineage dysplasia), and chronic myelomonocytic leukemia.}