Detail of EN27056240

Summary

    Name:XLYA_BACSU
    FullName:N-acetylmuramoyl-L-alanine amidase XlyA
    Producer Organism:Bacillus subtilis (strain 168)
    Sequence Length:297
    Mass:31913
    Calculated Isoelectric Point:
    Target:
    Link:P39800
    Function:Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation.

Domains

IPR002502:1-153

IPR018392:160-204

IPR002477:225-293

InterPro

100

150

200

250

297

  1  [1-153]:IPR002502,N-acetylmuramoyl-L-alanine amidase domain
  2  [160-204]:IPR018392,LysM domain
  3  [225-293]:IPR002477,Peptidoglycan binding-like?

GO term prediction

1 GO:0008745, the N-acetylmuramoyl-L-alanine amidase activity
2 GO:0009253, the peptidoglycan catabolic process

Structures

1
3HMBMethod:X-ray
Chains:A/B/C=1-154
2
3RDRMethod:X-ray
Chains:A=1-154

Sequence

MVNIIQDFIPVGANNRPGYAMTPLYITVHNTANTAVGADAAAHARYLKNPDTTTSWHFTV
DDTEIYQHLPLNENGWHAGDGNGSGNRASIGIEICENADGDFAKATANAQWLIKTLMAEH
NISLANVVPHKYWSGKECPRKLLDTWDSFKAGIGGGGSQTYVVKQGDTLTSIARAFGVTV
AQLQEWNNIEDPNLIRVGQVLIVSAPSAAEKPELYPLPDGIIQLTTPYTSGEHVFQVQRA
LAALYFYPDKGAVNNGIDGVYGPKTADAVARFQSVNGLTADGIYGPATKEKIAAQLS

BlastP to EnzyBase2

Activity

No MICs found on enzybiotics database

References

  [1]  Devine K.M.,Jorgensen S.T.,Krogh S.,  Lysis genes of the Bacillus subtilis defective prophage PBSX.  J. Bacteriol.,1998,(180):2110-2117  [PubMed:9555893]
  [2]  Alloni G.,Albertini A.M.,Moszer I.,Ogasawara N.,Kunst F.,  The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.  Nature,1997,(390):249-256  [PubMed:9384377]
  [3]  Karamata D.,Mauel C.,Longchamp P.F.,  Lytic enzymes associated with defective prophages of Bacillus subtilis: sequencing and characterization of the region comprising the N-acetylmuramoyl-L-alanine amidase gene of prophage PBSX.  Microbiology,1994,(140):1855-1867  [PubMed:7921239]