Detail of GM0018
Summary
The genetically modified enzybiotic, named CS74L1-177 , constructed by Truncation strategy, keep the lytic activity.With CS74L1-177
Sequence Length: 237 AA.
Mass: 25866 Da.
Isoelectric Point: 8.72
Function: exhibit lytic activity against cells of C. sporogenes.
Construction
GM0018, constructed by Truncation strategy. No schema construted on GM0018
Details:
GM0018[1-177]: derive from protein I1TJX3 sequence 1-177
I1TJX3, 264 AA., the Endolysin CS74L from Clostridium phage phi8074-B1
Source: Clostridium phage phi8074-B1
Molecular Function: 0008745, the N-acetylmuramoyl-L-alanine amidase activity?
Linking to UniprotKB
Linging to InterPro
Domains and repeats
2-167: IPR002508, the Cell wall hydrolase/autolysin, catalyticGO term prediction
Biological Process: 0009253, the peptidoglycan catabolic processMolecular Function: 0008745, the N-acetylmuramoyl-L-alanine amidase activity?
Linking to UniprotKB
Linging to InterPro
Annotation
1-177
1-177
: EAD, Amidase domain, derived from Lytic bacteriophage ATCC 8074-B1 endolysin CS74L;Domain and repeats:
2-167
: IPR002508,Cell wall hydrolase/autolysin, catalytic; GO term prediction:
0008745, the N-acetylmuramoyl-L-alanine amidase activity
0009253, the peptidoglycan catabolic process
MKIGIDMGHTLSGADYGVVGLRPESVLTREVGTKVIYKLQKLGHVVVNCTVDKASSVSESLYTRYYRANQANVDLFISIHFNATPGGTGTEVYTYAGRQLGEATRIRQEFKSLGLRDRGTKDGSGLAVIRNTKAKAMLVECCFCDNPNDMKLYNSESFSNAIVKGITGKLPNGESGNNNQGGNKVKAVVIYNEGADRRGAEYLADYLNCPTISNSRTFDYSCVEHVYAVGGKKEQYT