Detail of GM0027
Summary
The genetically modified enzybiotic, named S171 , constructed by Truncation strategy, lose the activities of cell targeting.With S171
Sequence Length: 171 AA.
Mass: 18668.3 Da.
Isoelectric Point: 10.01
Function: Zymogram activity show no zone of clearing
Construction
GM0027, constructed by Truncation strategy. No schema construted on GM0027
Details:
GM0027[1-171]: derive from protein I6X5A8 sequence 325-495
I6X5A8, 495 AA., the LysK from Staphylococcus phage Fi200W
Source: Staphylococcus phage Fi200W
196-369: IPR002502, the N-acetylmuramoyl-L-alanine amidase domain
409-481: IPR003646, the SH3-like domain, bacterial-type?
Linking to UniprotKB
Linging to InterPro
Domains and repeats
29-160: IPR007921, the CHAP domain196-369: IPR002502, the N-acetylmuramoyl-L-alanine amidase domain
409-481: IPR003646, the SH3-like domain, bacterial-type?
GO term prediction
Molecular Function: 0008745, the N-acetylmuramoyl-L-alanine amidase activityLinking to UniprotKB
Linging to InterPro
Annotation
1-171
93-156
: CBD, SH3b domain, derived from phage endolysin LysK;Domain and repeats:
85-157
: IPR003646,SH3-like domain, bacterial-type?; GO term prediction:
MEFVPTACPHRSMVLHTGFNPVTQGRPSQAIMNKLKDYFIKQIKNYMDKGTSSSTVVKDGKTSSASTPATRPVTGSWKKNQYGTWYKPENATFVNGNQPIVTRIGSPFLNAPVGGNLPAGATIVYDEVCIQAGHIWIGYNAYNGNRVYCPVRTCQGVPPNQIPGVAWGVFK