Detail of GM0039
Summary
The genetically modified enzybiotic, named lambdaSa2-E , constructed by Truncation strategy, decrease the lytic activity.With lambdaSa2-E
Sequence Length: 152 AA.
Mass: 16635.4 Da.
Isoelectric Point: 5.55
Function: showed very little activity in the turbidity reduction assay
Construction
GM0039, constructed by Truncation strategy. No schema construted on GM0039
Details:
GM0039[1-152]: derive from protein C5WI88 sequence 1-152
C5WI88, 449 AA., the Putative prophage LambdaSa2, lysin from Streptococcus dysgalactiae subsp. equisimilis (str
Source: Streptococcus dysgalactiae subsp. equisimilis (str
6-138: IPR000064, the Endopeptidase, NLPC/P60 domain
154-192: IPR013168, the Cpl-7 lysozyme, C-terminal?
198-236: IPR013169, the Cpl-7 lysozyme, C-terminal?
270-399: IPR002901, the Mannosyl-glycoprotein endo-beta-N-acetylglucosamid
Molecular Function: 0004040, the amidase activity?
Linking to UniprotKB
Linging to InterPro
Domains and repeats
5-145: IPR008044, the Bacteriophage lysin6-138: IPR000064, the Endopeptidase, NLPC/P60 domain
154-192: IPR013168, the Cpl-7 lysozyme, C-terminal?
198-236: IPR013169, the Cpl-7 lysozyme, C-terminal?
270-399: IPR002901, the Mannosyl-glycoprotein endo-beta-N-acetylglucosamid
GO term prediction
Biological Process: 0009253, the peptidoglycan catabolic processMolecular Function: 0004040, the amidase activity?
Linking to UniprotKB
Linging to InterPro
Annotation
1-152
1-148
: EAD, Endopeptidase domain, derived from Group B streptococcal prophage endolysin ??Sa2;Domain and repeats:
5-145
: IPR008044,Bacteriophage lysin; 6-138
: IPR000064,Endopeptidase, NLPC/P60 domain; GO term prediction:
MAIETEKAISWMVARQGAVSYSMDYRNGPSSYDCSSAIYYALMSAGTISAGWAVNTEYMHDWLIKNGYVLIAENQDWNSQRGDVVIWGLRGQSAGAGGHVVMFVDSDNIIHCNYANNGITINNYNQTAASAGWMYSYVYRLATPATTSTAGK