Detail of GM0047
Summary
The genetically modified enzybiotic, named LysgaYM233 , constructed by Truncation strategy, decrease the lytic activity.With LysgaYM233
Sequence Length: 233 AA.
Mass: 25189.9 Da.
Isoelectric Point: 7.39
Function: the cell-lytic ability is lower than that of LysgaY
Construction
GM0047, constructed by Truncation strategy. No schema construted on GM0047
Details:
GM0047[1-233]: derive from protein Q65YV6 sequence 1-233
Q65YV6, 310 AA., the Lysin from Lactobacillus phage phigaY
Source: Lactobacillus phage phigaY
235-305: IPR003646, the SH3-like domain, bacterial-type
Biological Process: 0009253, the peptidoglycan catabolic proces
Biological Process: 0016998, the peptidoglycan catabolic proces
Molecular Function: 0003796, the lysozyme activity
Linking to UniprotKB
Linging to InterPro
Domains and repeats
4-209: IPR013781, the Glycoside hydrolase, catalytic domain235-305: IPR003646, the SH3-like domain, bacterial-type
GO term prediction
Biological Process: 0005975, the carbohydrate metabolic processBiological Process: 0009253, the peptidoglycan catabolic proces
Biological Process: 0016998, the peptidoglycan catabolic proces
Molecular Function: 0003796, the lysozyme activity
Linking to UniprotKB
Linging to InterPro
Annotation
1-233
1-206
: EAD, domain, derived from Lactobacillus gasseri JCM 1131T phage ??gaY endolysin,LysgaY;217-310
: CBD, SH3bgaY domain, derived from Lactobacillus gasseri JCM 1131T phage ??gaY endolysin,LysgaY;Domain and repeats:
4-209
: IPR013781,Glycoside hydrolase, catalytic domain; GO term prediction:
0005975, the carbohydrate metabolic process
MVEVAKRSYGVDVSSHNNGNYSGSKFAVVKVSEGLDYRNPKAQSQVSTARANSMLPMAYHYARFSGNSNVAIQEGNYAVTSAKAVGLEAGTYLACDYEQGSGNETRGDRETNTTAILSFLDTIVGAGYKPLLYSGAYLMRDKINTSRILAKYPNCLWVAAYPSGNGTAVSEPNFGYFPSMNGVAIWQFTDNWRGLNVDGNISLIDLKNDSKPVAQPSVAQSASEKTWTDVQGM