Detail of GM0094
Summary
The genetically modified enzybiotic, named Lg284-2 , constructed by Mutagenesis strategy, decrease the lytic activity.With Lg284-2
Sequence Length: 310 AA.
Mass: 33572.1 Da.
Isoelectric Point: 8.55
Function: decrease the lytic activity
Construction
GM0094, constructed by Mutagenesis strategy. No schema construted on GM0094
Details:
GM0094[1-310]: derive from protein Q65YV6 sequence 1-310
Q65YV6, 310 AA., the Lysin from Lactobacillus phage phigaY
Source: Lactobacillus phage phigaY
235-305: IPR003646, the SH3-like domain, bacterial-type
Biological Process: 0009253, the peptidoglycan catabolic proces
Biological Process: 0016998, the peptidoglycan catabolic proces
Molecular Function: 0003796, the lysozyme activity
Linking to UniprotKB
Linging to InterPro
Domains and repeats
4-209: IPR013781, the Glycoside hydrolase, catalytic domain235-305: IPR003646, the SH3-like domain, bacterial-type
GO term prediction
Biological Process: 0005975, the carbohydrate metabolic processBiological Process: 0009253, the peptidoglycan catabolic proces
Biological Process: 0016998, the peptidoglycan catabolic proces
Molecular Function: 0003796, the lysozyme activity
Linking to UniprotKB
Linging to InterPro
Annotation
1-310
1-206
: EAD, domain, derived from Lactobacillus gasseri JCM 1131T phage ??gaY endolysin,LysgaY;217-310
: CBD, SH3bgaY domain, derived from Lactobacillus gasseri JCM 1131T phage ??gaY endolysin,LysgaY;284
: MUT, mutation with W284G ;Domain and repeats:
235-305
: IPR003646,SH3-like domain, bacterial-type; 4-209
: IPR013781,Glycoside hydrolase, catalytic domain; GO term prediction:
0005975, the carbohydrate metabolic process
MVEVAKRSYGVDVSSHNNGNYSGSKFAVVKVSEGLDYRNPKAQSQVSTARANSMLPMAYHYARFSGNSNVAIQEGNYAVTSAKAVGLEAGTYLACDYEQGSGNETRGDRETNTTAILSFLDTIVGAGYKPLLYSGAYLMRDKINTSRILAKYPNCLWVAAYPSGNGTAVSEPNFGYFPSMNGVAIWQFTDNWRGLNVDGNISLIDLKNDSKPVAQPSVAQSASEKTWTDVQGMTWHEEHGTFITGGAINLRWGANTQSTLITTLPAGSEVKYNAWARDSAGRVGLQQPRENGKNGYLVGRVGSEPWGTFK