Detail of GM0174
Summary
The genetically modified enzybiotic, named EAD118_III_CBDPSA , constructed by Domains Assembly strategy, improve the lytic activity.With EAD118_III_CBDPSA
Sequence Length: 276 AA.
Mass: 31554.8 Da.
Isoelectric Point: 10.21
Function:
Construction
GM0174, constructed by Domains Assembly strategy. No schema construted on GM0174
Details:
GM0174[1-133]: derive from protein Q37976 sequence 1-113
Q37976, 281 AA., the L-alanyl-D-glutamate peptidase from Listeria phage A118 (Bacteriophage A118)
Source: Listeria phage A118 (Bacteriophage A118)
153-193: IPR022016, the Domain of unknown function DUF3597
Linking to UniprotKB
Linging to InterPro
Domains and repeats
8-121: IPR009045, the Hedgehog signalling/DD-peptidase zinc-binding doma153-193: IPR022016, the Domain of unknown function DUF3597
GO term prediction
No GO info found on GM0174Linking to UniprotKB
Linging to InterPro
GM0174[134-276]: derive from protein Q8W5Y8 sequence 172-314
Q8W5Y8, 314 AA., the Ply protein from Listeria phage PSA
Source: Listeria phage PSA
Linking to UniprotKB
Linging to InterPro
Domains and repeats
No sequence info found on GM0174GO term prediction
No GO info found on GM0174Linking to UniprotKB
Linging to InterPro
Annotation
1-133
134-276
1-133
: EAD, L-alanoyl-D-glutamate peptidase domain, derived from Listeria phage endolysin Ply118;134-276
: CBD, CBDPSA domain, derived from L. monocytogenes PSA endolysin PlyPSA;Domain and repeats:
GO term prediction:
MTSYYYSRSLANVNKLADNTKAAARKLLDWSESNGIEVLIYETIRTKEQQAANVNSGASQTMRSYHLVGQALDFVMAKGKTVDWGAYRSDKGKKFVAKAKSLGFEWGGDWSGFVDNPHLQFNYKGYGTDTFGK-TGKTVAAKNPNRHSGAVVDSVPMLSKMDFKSSPIKMYKAGSSLLVYEHNKYWYKAYINDKLCYIYKSFCISNGKKDAKGRIKVRIKSAKDLRIPVWNNTKLNSGKIKWYSPGTKLSWYDNKKGYLELWY EKDGWYYTANYFLK