Record in detail

lamp_id:L01A000103
Name:CR118_LITGR
FullName:Caerin-1.18
Source:Litoria gracilenta
Mass:2624.2 Da
Sequence Length:25 aa
Isoelectric Point:9.54
Activity:Antibacterial
Sequence
GLFSVLGSVAKHLLPHVVPVIAEKL
Function:Shows significant activity against Gram-positive organisms, but is less effective against Gram-negative organisms.

Top similar AMPs on LAMP
1. L01A000103 From 1 To 25 E-value: 0.00000003 Score: 48.9
GLFSVLGSVAKHLLPHVVPVIAEKL
2. L13A015909 From 1 To 24 E-value: 0.00000007 Score: 47.8
GLFSVLGSVAKHLLPHVVPVIAEK
3. L13A023566 From 1 To 25 E-value: 0.00000009 Score: 47.4
GLFKVLGSVAKHLLPHVVPVIAEKL
4. L01A000102 From 1 To 25 E-value: 0.00000009 Score: 47.4
GLFSVLGSVAKHLLPHVAPIIAEKL
5. L01A000528 From 1 To 25 E-value: 0.0000001 Score: 46.6
GLFSVLGAVAKHVLPHVVPVIAEKL

Antibacterial Activities
1 Target: Bacillus cereus MIC: 50 μg/ml (19.0534 μM)
2 Target: Leuconostoc lactis MIC: 25 μg/ml (9.52671 μM)
3 Target: Listeria innocua MIC: 12 μg/ml (4.57282 μM)
4 Target: Micrococcus luteus MIC: 12 μg/ml (4.57282 μM)
5 Target: Staphylococcus aureus ATCC 25923 MIC: 12 μg/ml (4.57282 μM)
6 Target: Staphylococcus aureus ATCC 29213 MIC: 12 μg/ml (4.57282 μM)
7 Target: Staphylococcus epidermidis MIC: 25 μg/ml (9.52671 μM)
8 Target: Streptococcus uberis MIC: 25 μg/ml (9.52671 μM)
9 Target: Pasteurella multocida MIC: 50 μg/ml (19.0534 μM)

Reference
[1] Doyle J.R.,Bowie J.H.,Bilusich D.,Brinkworth C.S.,Maclean M.J.,
Title:New caerin antibiotic peptides from the skin secretion of the dainty green tree frog Litoria gracilenta. Identification using positive and negative ion electrospray mass spectrometry.
Journal:Toxicon, 2006, 47, 664-675 [PubMed:16554081]