Record in detail


General Info

  • lamp_id:L01A000112
  • Name:RNS2C_RANSV
  • FullName:Ranatuerin-2SEc
  • Source:Rana sevosa
  • Mass:2935.6 Da
  • Sequence Length:28 aa
  • Isoelectric Point:9.55
  • Activity:Antibacterial
  • Sequence
        GIMDTIKDTAKTVAVGLLNKLKCKITGC
  • Function:Mast cell degranulating peptide. Causes histamine release from rat peritoneal mast cells in vitro. Has antibacterial activity against the Gram-negative bacterium E.coli K12 and Gram-positive bacterium M.luteus NCT C2665.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000112    From 1 To 28 E-value: 0.0000000004 Score: 55.5
        GIMDTIKDTAKTVAVGLLNKLKCKITGC
  • 2. L01A000111    From 1 To 28 E-value: 0.000000001 Score: 53.5
        AIMDTIKDTAKTVAVGLLNKLKCKITGC
  • 3. L02A001505    From 1 To 28 E-value: 0.000000003 Score: 52.4
        GIMDTIKDTAKTVAVGLLDKIKCKITGC
  • 4. L02A001506    From 1 To 28 E-value: 0.000000009 Score: 50.8
        GIMDTIKNTAKTVAVGLLDKIKCKITGC
  • 5. L02A001275    From 1 To 28 E-value: 0.0000002 Score: 46.6
        GILDTIKNAAKTVAVGLLEKIKCKMTGC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Flatt P.R.,O"Kane E.,McClean S.,Richter S.C.,Graham C.,
  •   Title:Histamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosa.
  •   Journal:Peptides, 2006, 27, 1313-1319  [PubMed:16386333]

Comments

  •   Comments

    •     No comments found on LAMP database



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