Record in detail

General Info

lamp_id:L01A000435
Name:BR1LA_RANLU
FullName:Brevinin-1La
Source:Rana luteiventris
Mass:2548.3 Da
Sequence Length:24 aa
Isoelectric Point:9.67
Activity:Antibacterial
Sequence
FLPMLAGLAASMVPKLVCLITKKC
Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli.

Cross-Linking

Cross-linking
1 Database:APD 461
2 Database:CAMP CAMPSQ402
3 Database:DBAASP 3585
4 Database:dbAMP dbAMP_02147
5 Database:DRAMP DRAMP02089
6 Database:SATPdb satpdb11064
7 Database:Uniprot P82825
8 Database:AMD BR1LA_RANLU

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000435 From 1 To 24 E-value: 0.00000004 Score: 48.5
FLPMLAGLAASMVPKLVCLITKKC
2. L01A000436 From 1 To 24 E-value: 0.0000001 Score: 47
FLPMLAGLAASMVPKFVCLITKKC
3. L11A013306 From 1 To 24 E-value: 0.000004 Score: 42
FLPILAGLAANLVPKLICSITKKC
4. L02A001723 From 1 To 24 E-value: 0.000005 Score: 41.6
FFPMLAGVAARVVPKVICLITKKC
5. L13A010541 From 1 To 24 E-value: 0.000007 Score: 40.8
FLPMLAGLAANFLPKIVCKITKKC

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities
1 Target: E. coli MIC: 127.415 μg/ml (50 μM)
2 Target: S. aureus MIC: 15.2898 μg/ml (6 μM)

Toxicity

Toxicity

Reference

Reference
[1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]

Comments

Comments