Record in detail


General Info

  • lamp_id:L01A000454
  • Name:DDQ1_PHYDS
  • FullName:Dermadistinctin-Q1
  • Source:Phyllomedusa distincta
  • Mass:2996.6 Da
  • Sequence Length:30 aa
  • Isoelectric Point:10.8
  • Activity:Antibacterial
  • Sequence
        ALWKNMLKGIGKLAGQAALGAVKTLVGAES
  • Function:Antibacterial activity against Gram-positive bacteria S.aureus and E.faecalis, and Gram-negative bacteria P.aeruginosa and E.coli.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A06201|    From 46 To 74 E-value: 0.00000000007 Score: 57.8
        ALWKNMLKGIGKLAGQAALGAVKTLVGAE
  • 2. L01A000454    From 1 To 30 E-value: 0.00000000009 Score: 57.4
        ALWKNMLKGIGKLAGQAALGAVKTLVGAES
  • 3. L02A000165    From 1 To 29 E-value: 0.0000000003 Score: 55.5
        ALWKNMLKGIGKLAGQAALGAVKTLVGAE
  • 4. L01A000499    From 1 To 30 E-value: 0.000000002 Score: 53.1
        ALWKNMLKGIGKLAGKAALGAVKKLVGAES
  • 5. L01A000151    From 1 To 28 E-value: 0.000000002 Score: 53.1
        ALWKNMLKGIGKLAGQAALGAVKTLVGA

Structure

  •   Domains
  •   1  Name:Dermaseptin    Interpro Link:IPR022731
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E. coli  MIC:  3.89558 μg/ml  (1.3 μM)  
  •   2  Target:  S. aureus  MIC:  8.09082 μg/ml  (2.7 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Ferrara L.,Scaloni A.,Sebben A.,da Silva L.R.,Batista C.V.F.,
  •   Title:Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta.
  •   Journal:Peptides, 1999, 20, 679-686  [MEDLINE:99404773]

Comments

  •   Comments

    •     No comments found on LAMP database



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