Record in detail


General Info

  • lamp_id:L05ADEF181
  • Name:DEF7_PANTR
  • FullName:Defensin-7
  • Source:Pan troglodytes
  • Mass:10362.8 Da
  • Sequence Length:94 aa
  • Isoelectric Point:4.93
  • Activity:Antimicrobial
  • Sequence
        MRTLTLLSAFLLVALQAWAEPLQARADEMPAQKQPPADDQDVVIYFSGDDSSSLQVPGSTKGLICHCRVLYCLFGEHLGGTSFIHGERYPICCY
  • Function:Has antimicrobial activity (By similarity).

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  Q5G859
  •   2  Database:DEF  DEF181

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L05ADEF181    From 1 To 94 E-value: 0 Score: 196
        MRTLTLLSAFLLVALQAWAEPLQARADEMPAQKQPPADDQDVVIYFSGDDSSSLQVPGSTKGLICHCRVLYCLFGEHLGGTSFIHGERYPICCY
  • 2. L01A003547    From 1 To 75 E-value: 9.99967e-42 Score: 160
        EPLQARADEMPAQKQPPADDQDVVIYFSGDDSSSLQVPGSTKGLICHCRVLYCLFGEHLGGTSFIHGERYPICCY
  • 3. L05ADEF188    From 1 To 93 E-value: 1e-21 Score: 93.6
        MRTIAILAAILLVALQAQAESLQERADEATTQKQSGEDNQDLAISFAGNGLSALRTSGSQARATCYCRIGHCTILESLSGVCEISGRLYRLCC
  • 4. L03A000275    From 1 To 93 E-value: 3e-21 Score: 92
        MRTIAILAAILLVALQAQAESLQERADEATTQKQSGEDNQDLAISFAGNGLSALRTSGSQARATCYCRTGRCATRESLSGVCEISGRLYRLCC
  • 5. L12A09198|    From 1 To 93 E-value: 5e-21 Score: 91.3
        MRTIAILAAILLVALQAQAESLQERADEAATQKQSGEDNQDLAVSFAGNGLSTLRASDSQARSTCYCRIGLCAAIESYSGRCYISGRRYRLCC

Structure

  •   Domains
  •   1  Name:Alpha-defensin    Interpro Link:IPR016327
  •   2  Name:Defensin_propep    Interpro Link:IPR002366
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Zhang G.,Hughes A.L.,Patil A.,
  •   Title:Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes.
  •   Journal:Physiol. Genomics, 2004, 20, 1-11  [PubMed:15494476]

Comments

  •   Comments

  •     No comments found on LAMP database



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