Record in detail


General Info

  • lamp_id:L01A000007
  • Name:PHY12_PHYAZ
  • FullName:Phylloseptin-12
  • Source:Phyllomedusa azurea
  • Mass:2000.4 Da
  • Sequence Length:20 aa
  • Isoelectric Point:10.8
  • Activity:Antibacterial
  • Sequence
        FLSLLPSIVSGAVSLAKKLG
  • Function:Has antibacterial activity against the Gram-positive bacterium M.luteus ATCC 49732 (MIC=1.3 uM). Does not inhibit the growth of the fungus C.albicans.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A06078|    From 38 To 57 E-value: 0.00001 Score: 40
        FLSLLPSIVSGAVSLAKKLG
  • 2. L01A000007    From 1 To 20 E-value: 0.00005 Score: 37.7
        FLSLLPSIVSGAVSLAKKLG
  • 3. L02A000977    From 1 To 19 E-value: 0.0002 Score: 35.8
        FLSLLPSIVSGAVSLAKKL
  • 4. L13A016316    From 1 To 18 E-value: 0.0006 Score: 34.3
        FLSLLPSIVSGAVSLAKK
  • 5. L02A000975    From 1 To 19 E-value: 0.002 Score: 32.7
        FLSLLPSLVSGAVSLVKKL

Structure

  •   Domains
  •   1  Name:Brevinin    Interpro Link:IPR004275
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  M. luteus ATCC 49732  MIC:  2.6 μg/ml  (1.29974 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  McClean S.,Shaw C.,Orr D.F.,Bjourson A.J.,Thompson A.H.,
  •   Title:A combined mass spectrometric and cDNA sequencing approach to the isolation and characterization of novel antimicrobial peptides from the skin secretions of Phyllomedusa hypochondrialis azurea.
  •   Journal:Peptides, 2007, 28, 1331-1343  [PubMed:17553595]

Comments

  •   Comments

    •     No comments found on LAMP database



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