Record in detail
General Info
- lamp_id:L01A000008
- Name:PLEUR_PLEOS
- FullName:Pleurostatin
- Source:Pleurotus ostreatus
- Mass:964.2 Da
- Sequence Length:8 aa
- Isoelectric Point:9.34
- Activity:Antifungal
- Sequence
VRPYLVAF - Function:Antifungal activity. Inhibits mycelial growth of F.oxysporum, M.oxysporum and P.piricola. Inhibits cell-free translation with an IC(50) of 28 uM. Antiproliferative activity against MBL2 and L1210 tumor cell lines in vitro.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ6
- 2 Database:dbAMP dbAMP_11894
- 3 Database:DRAMP DRAMP03474
- 4 Database:SATPdb satpdb13488
- 5 Database:Uniprot P84866
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000008 From 1 To 8 E-value: 7.4 Score: 19.2
VRPYLVAF
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: 20 % growth inhibition F. oxysporum MIC: 15.04 μg/ml (15.5984 μM)
- 2 Target: 45 % growth inhibition M. arachidicola MIC: 15.04 μg/ml (15.5984 μM)
- 3 Target: 63 % growth inhibition P. piricola MIC: 15.04 μg/ml (15.5984 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Ng T.B.,Xia L.,Chu K.T.,
- Title:Pleurostrin, an antifungal peptide from the oyster mushroom.
- Journal:Peptides, 2005, 26, 2098-2103 [PubMed:15941607]
Comments
- Comments
No comments found on LAMP database