Record in detail

General Info

lamp_id:L01A000015
Name:MASTA_POLDO
FullName:Dominulin-A
Source:Polistes dominula
Mass:1856.2 Da
Sequence Length:17 aa
Isoelectric Point:10.51
Activity:Antibacterial
Sequence
INWKKIAEVGGKILSSL
Function:Shows antimicrobial activity against the Gram-positive bacteria B.subtilis ATCC 6633 (MIC=2 ug/ml), and the Gram-negative bacteria E.coli JM109 (MIC=8 ug/ml).

Cross-Linking

Cross-linking
1 Database:APD 1638
2 Database:CAMP CAMPSQ13
3 Database:DBAASP 502
4 Database:dbAMP dbAMP_04814
5 Database:DRAMP DRAMP03050
6 Database:SATPdb satpdb19372
7 Database:Uniprot P0C1M6

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000015 From 1 To 17 E-value: 0.0004 Score: 34.7
INWKKIAEVGGKILSSL
2. L13A011077 From 1 To 16 E-value: 0.001 Score: 33.1
INWKKIAEVGGKILSS
3. L01A000017 From 1 To 17 E-value: 0.019 Score: 29.3
INWKKIAEIGKQVLSAL
4. L13A019087 From 1 To 16 E-value: 0.059 Score: 27.3
INWKKIAEIGKQVLSA
5. L02A001637 From 1 To 17 E-value: 0.38 Score: 24.6
INWKKIASIGKEVLKAL

Structure

Domains

Structures

Activity

Antibacterial Activities
1 Target: B. subtilisATCC 6633 MIC: 2 μg/ml (1.07747 μM)
2 Target: E. coli JM109 MIC: 8 μg/ml (4.30988 μM)

Toxicity

Toxicity

Reference

Reference
[1] Pieraccini G.,Moneti G.,Dani F.R.,Mastrobuoni G.,Turillazzi S.,
Title:Dominulin A and B: two new antibacterial peptides identified on the cuticle and in the venom of the social paper wasp Polistes dominulus using MALDI-TOF, MALDI-TOF/TOF, and ESI-ion trap.
Journal:J. Am. Soc. Mass Spectrom., 2006, 17, 376-383 [PubMed:16446098]

Comments

Comments